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胰糜蛋白酶6:1

胰糜蛋白酶6:1

更新时间:2019-11-19
CAS号:9002-07-7
药典:中国药典,美国药典,英国药典,欧洲药典,企业标准
级别:食品级,药用级
详细描述
  • 包装规格:铝听,纸板桶
  • 付款方式:L/C D/A D/P T/T
  • 订单交货周期:5 days after receiving purchase order
  • 主要销售市场:北美洲,中/南美洲,西欧,东欧,大洋洲,亚洲,中东,非洲
  • 提供样品:
  • 样品政策: free
产品描述:

Trypsin 

Source: Bovine (Porcine) pancreas

General description

Trypsin is a kind of serine protein hydrolase, exclusive role in composed of alkaline amino acids arginine and leucine peptide bond, soluble in **, insoluble in chloroform, ethanol, ethyl ether, and glycerin, Ca2 + is protection for trypsin and activation function.

Manufacture

Trypsin production of Beijing Geyuantianrun Bio - tech Co., ltd. is by protein chromatography technology preparation, reach the standard pharmaceutical raw materials.

Application

  • As pharmaceutical raw materials manufacturing injection, infusion agent, sprays, clinical surgery used for all sorts of inflammation, ulcers, gangrene, an abscess caused by trauma, impotent, edema, hematoma and snake bites. Surgery for the treatment of tinea scabies and other skin disorders. Internal medicine for pyothorax, emphysema, bronchitis, bronchus wheeze, etc; Treatment of diabetic complications, such as nephritis; Treatment of bone disease.
  • As a food processing cutting big molecular protein.
  • As a proteolytic enzyme is widely applied in biology, medicine and food industries research and development, testing field.

Specification 

Items

Specification

Standard

Appearance

White or almost white lyophilized powder

USP35

Solubility

500,000USP Trypsin Units is soluble in 10ml of ** and in

10ml of saline TS.

USP35

Loss on drying

No more than 5.0%

USP35

Residue on Ignition

No more than 2.5%

USP35

Microbial limits:

Pseudomonas aeruginosa

Salmonella

Staphylococcus aureus

Absent

USP35

Chymotrypsin

No more than 50 USP units/mg powder

USP35

Assay

Trypsin ≥ 2500USP units/mg powder

USP35

 

 

 

Items

Specification

Standard

Description

white crystalline powder

EP6.0

Identification

A) A purple color develops within 3 minutes

B) No purple color develops with in 3 minutes

EP6.0

Appearance of solution

Solution S is not more opalescent than reference suspension Ⅲ

EP6.0

Absorbance

1) 280nm : 13.5 ~ 16.5

2) 250nm : not more than 7.0

EP6.0

PH

3.0-6.0

EP6.0

Histamine

Not more than 1µg/0.2µkatal

EP6.0

Loss on drying

Not more than 5%

EP6.0

Limit of chymotrypsin

Not more than 1%

EP6.0

Microbial limits

Total viable aerobic count

Salmonella  

E.Coli

 

≤10000cfu/g

Absent

Absent

EP6.0

Assay

Not less than 0.5µkatal /mg, calculated on the dried basis.

EP6.0

来源:猪(牛)胰腺        

概述

胰糜蛋白酶是糜蛋白酶和胰蛋白酶的混合晶体,具有两种酶的性质。水解酪蛋白的活力与糜蛋白酶相当,水解苯甲酰酪氨酸乙酯的活力相当于糜蛋白酶的3倍,水解酯键的活力与胰蛋白酶相似。干燥情况下稳定,液体状态易失活,PH7—8时活性**强。

北京格源天润生物技术有限公司生产的糜胰蛋白酶是通过多重结晶方式纯化,并进一步采取超滤技术制备而得。

用途

  • 临床于**各种炎症、炎性水肿、血肿、术后粘连、溃疡、血栓等,对慢性**、**、胃炎、宫颈炎、盆腔炎、化脓性中耳炎、前列腺炎、栓塞性静脉炎、脑血栓形成等均有一定疗效。
  • 应用于现代工业领域,如作为高级皮革的脱毛、软化剂。
  • 作为实验室分析试剂,被科研院校广泛应用。
  • 动物细胞培养前对组织的处理

    质量规格 6:1

    项目

     规格

    执行标准

    性状

    白色或类白色粉末

          企业标准

    灼烧残渣

    不得超过2.5%

    美国药典37版

    干燥失重

    不得超过5.0%

    美国药典37版

    效价测定

     胰蛋白酶 ≥ 2400单位/毫克

    糜蛋白酶 ≥ 400单位/毫克

    企业标准

 

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