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Dexrazoxane CAS 24584-09-6
Chemical PropertiesMolecular Weight: 268.27 Density: 1.333 g/cm3 Boiling Point: 531.5 °C at 760 mmHg Melting Point: 194-196℃ Flash Point: 531.5 °C at 760 mmHg Refractive index: 1.539 Solubility: Slightly soluble in methanol and ethanol. Insoluble in non polar organic solvents. Biological Activity: Topoisomerase II inhibitor and intracellular ion chelator. Bridges and stabilizes an interface between two ATPase promoters to inhibit topoisomerase II activity. Cardioprotective when co-administered with doxorubicin; decreases formation of reactive oxygen species (ROS) and activates the PI3K/Akt survival pathway. Safety Data of 24584-09-6
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