白色类白色粉末

前列腺素E1 (前列地尔) Alprostadil CAS NO:745-65-3 纯度：98%以上 现货。

前列腺素E1（ProstaglandinE1）又名前列地尔、保达新、**和凯威捷。前列腺素E1是广泛存在于体内的生物活性物质，为前列腺素家族中的一员，是一种公认的内源性生理活性物质。前列腺素E1直接作用于血管平滑肌，扩张血管，提高血流量，改善微循环灌注；并抑制血小板聚集和血栓素A2生成，抑制动脉粥样硬化、脂质斑与免疫复合物Chemicalbook形成;扩张外周小血管和冠状动脉，降低外周血管阻力与血压，保护血小板细胞膜，防止血栓形成;保护缺血心肌，缩小心肌梗死面积;抗心力衰竭；扩张肾血管，增加肾血流量，清除非蛋白氮，调节水钠平衡，具有利尿和保护肾功能的作用。t1/2为5～10min。68%经肝代谢后由肾排出。临床用于冠心病心绞痛、心肌梗死、肺动脉高压、慢性动脉闭塞等

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医药

USP/EP

 For more about us , please visit our site: https://afinechem.en.alibaba.com or https://afinepharm.en.alibaba.com/   high quality Alprostadil 99% CAS 745-65-3,active pharmaceutical ingredient         Chemical Properties Appearance: white to off-white crystalline powder Molecular Weight: 354.48 Density: 1.131 g/cm3 Boiling Point: 529.3 °C at 760 mmHg Melting Point: 115-116℃ Flash Point: 288 °C Alpha: -64 o (C=1.0, C2H5OH) Storage Temperature: ?20°C Solubility: insoluble in ** Biological Activity: Prostaglandin with some selectivity for EP 3 and EP 4 receptors (K i values are 1.1, 2.1, 36, 10? and 33 nM for mouse EP 3 , EP 4 , EP 1 , EP 2 and IP receptors respectively). Inhibits platelet aggregation and is a vasodilator in vivo . Stability: Stable under normal temperatures and pressures. Usage: A primary Prostaglandin; easily crystallized from purified biological extracts. Vasodilator (peripheral) Safety Data of 745-65-3