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361442-04-8
361442-04-8结构式361442-04-8结构式
目录
基本信息
[英文名称]

(1S,3S,5S)-2-[2(S)-Amino-2-(3-hydroxyadamantan-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile

[英文别名]

Saxagliptin; BMS 477118; Onglyza; (1S,3S,5S)-2-[(2S)-2-amino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile

[CAS]

361442-04-8

[分子式]

C18H25N3O2

[分子量]

315.41

[沸点]

548.7°C at 760 mmHg

[密度]

2.51E-14mmHg at 25°C

[闪点]

285.6°C

CAS号码361442-04-8 推荐供应商
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Saxagliptin inhibits dipeptidyl peptidase 4 (DPP-4) enzyme resulting in prolonged active incretin levels. Incretin hormones (eg, glucagon-like peptide-1, glucose-dependent insulinotropic polypeptide) regulate glucose homeostasis by increasing insulin synthesis and release from pancreatic beta cells and decreasing glucagon secretion from pancreatic alpha cells. Decreased glucagon secretion results in decreased hepatic glucose production. Under normal physiologic circumstances, incretin hormones are released by the intestine throughout the day and levels are increased in response to a meal; incretin hormones are rapidly inactivated by the DPP-4 enzyme.
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品名:沙格列汀 CAS#:361442-04-8 含量:98.5%以上 包装:铝箔袋,纸板桶 注意:该产品仅供研发使用,不做销售。
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CAS: 361442-04-8   产品名称: 沙格列汀 英文名:Saxagliptin 分子式:C18H25N3O2 分子量:315.414
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