Metoprolol tartrate

更新时间：2018-03-28

CAS号：56392-17-7

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Metoprolol tartrate 99% CAS NO.:56392-17-7,active pharmaceutical ingredient

Chemical Properties Appearance: white to off-white / powder Molecular Weight: 684.81464 Density: g/cm³ Boiling Point: 398.6 °C at 760 mmHg Melting Point: 120 C Flash Point: 194.9 °C Storage Temperature: Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage. Solubility: H2O: 50 mg/mL Biological Activity: Selective β 1 -adrenoceptor antagonist (K i values are 47, 2960 and 10100 nM for β 1 , β 2 and β 3 adrenoceptors respectively). Inhibits spontaneous endothelin-1 production in vitro and displays antihypertensive and antianginal activity in vivo . Stability: Stable. Incompatible with strong oxidizing agents. Usage: A ? selective aryloxypropanolamine andrenergic antagonist. Used in the treatment of a variety of cardiovascular disorder. Antihypertensive; antianginal; antiarrhythmic (class II) Safety Data of 56392-17-7

Chemical Properties

Appearance:

white to off-white / powder

Molecular Weight:

684.81464

Density:

g/cm³

Boiling Point:

398.6 °C at 760 mmHg

Melting Point:

120 C

Flash Point:

194.9 °C

Storage Temperature:

Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.

Solubility:

H2O: 50 mg/mL

Biological Activity:

Selective β 1 -adrenoceptor antagonist (K i values are 47, 2960 and 10100 nM for β 1 , β 2 and β 3 adrenoceptors respectively). Inhibits spontaneous endothelin-1 production in vitro and displays antihypertensive and antianginal activity in vivo .

Stability:

Stable. Incompatible with strong oxidizing agents.

Usage:

A ? selective aryloxypropanolamine andrenergic antagonist. Used in the treatment of a variety of cardiovascular disorder. Antihypertensive; antianginal; antiarrhythmic (class II)