H3-K27me1

序列：ARTKQTARKS TGGKAPRKQL ATKAARK(me1)SAP ATGGVKKPHR YRPGTVALRE IRRYQKSTEL LIRKLPFQRL
VREIAQDFKT DLRFQSSAVM ALQEACEAYL VGLFEDTNLC AIHAKRVTIM PKDIQLARRI RGERA

Histone modifications are associated with distinct transcription states and serve as heritable epigenetic markers for chromatin structure and function.Histone H3K27 methylation mediated by the PRC2 complex is critical for transcriptional regulation, Polycomb silencing, Drosophila segmentation, mammalian X inactivation and cancer.