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Adapalene CAS 106685-40-9
Appearance:
white to off-white crystalline powder
Molecular Weight:
412.52
Density:
1.233 g/cm3
Boiling Point:
606.3 °C at 760 mmHg
Melting Point:
319-322 °C
Flash Point:
205.9 °C
Storage Temperature:
Store in original container in a cool dark place.
Refractive index:
1.654
Solubility:
Insoluble
Biological Activity:
Retinoic acid analog that is a RAR β and RAR γ agonist (AC 50 values are 2.2, 9.3, 22 and > 1000 nM for RAR β , RAR γ , RAR α and RXR α receptors respectively). Inhibits proliferation and induces apoptosis in colorectal cancer cell in vitro . Displays comedolytic activity.
Usage:
Retinoid selective for retinoic acid receptor (RAR) subtypes ?and . Antiacne
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106685-40-9结构式
