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Clarithromycin/CAS No.:81103-11-9
1.CAS NO.:81103-11-9
2.Color:white powder
3.Standard:usp
4.paking:25kg/drum
5. Appearance: White or almost white crystalline powder , No odor and bitter.Insoluble in water, freely soluble in chloroform, soluble in acetone or ethyl acetate, sparingly soluble in methanol of alcohol.
6. indications:
Mainly used for caused by sensitive bacteria upper and lower respiratory tract, including tonsil inflammation, sore throat, deputy sinusitis, bronchitis, pneumonia, etc, skin, soft tissue infection, pus furuncle, erysipelas, folliculitis, wound infection and so on, curative effect and other large ring lactone class similar. The goods can also be used to chlamydia trachomatis or dissolved ureaplasma urealyticum reproduction caused by urinary tract infection, AIDS patients with atypical mycobacteria infection.
| Appearance | White or almost white crystalline powder, No odor and bitter.Insoluble in water, freely soluble in chloroform, soluble in acetone or ethyl acetate, sparingly soluble in methanol of alcohol. | Conforms |
| Identification Tests (IR) | Conforms to the reference spectrum | Conforms |
| Specific optical rotation | -89°-95° | -92° |
| Crystallinity | Should conform to requirements | Conforms |
| PH | Between 7.5 and 10.0 | 8.8 |
| Water | ≤2.0% | 0.72% |
| Residue on ignition | ≤0.3% | 0.04% |
| Residual Solvents | Ethanol≤0.5% | Not detected |
| Heavy metals | ≤20ppm | <20ppm |
| Assay (HPLC, dried substance) | 9601040ug/mg | 981ug/mg |
| Conclusion: Conforms to USP 28 specification for Clarithromycin | ||
ClarithromycinCAS号：81103-11-9
Clarithromycin分子式： C38H69NO13
Clarithromycin英文名称： Clarithromycin
Clarithromycin英文同义词： 6-O-Methylerythromycin; A-56268; Biaxin; Klacid; TE-03; (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-12,13-dihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-7-methoxy-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione (non-preferred name); (3R,4S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-12,13-dihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-7-methoxy-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione (non-preferred name)
Clarithromycin分子量： 747.9534
Clarithromycin熔点： 217-220℃
Clarithromycin沸点： 805.5°C at 760 mmHg
Clarithromycin密度： 5.06E-30mmHg at 25°C
Clarithromycin闪点： 440.9°C
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