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797-63-7
797-63-7结构式797-63-7结构式
目录
基本信息
[英文名称]

D(minus)-norgestrel

[英文别名]

Levonorgestrel; Norgestrel (L-); 13-ethyl-17-alpha-ethynyl-17-beta-hydroxy-4-gonen-3-one; 13-ethyl-17-alpha-ethynylgon-4-en-17-beta-ol-3-one; 13-ethyl-17-hydroxy-19-dinor-17-alpha-pregn-4-en-20-yn-3-on(+)-1; 17-alpha-ethinyl-13-beta-ethyl-17-beta-hydroxy-4-estren-3-one; 17-beta-hydroxy-18-methyl-19-nor-17-alpha-pregn-4-en-20-yn-3-one; 17-ethynyl-18-methyl-19-nortestosteron; 17-ethynyl-18-methyl-19-nortestosterone; 18-methyl-17-alpha-ethynyl-19-nortestosterone; (14S,17R)-13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one (non-preferred name)

[CAS]

797-63-7

[EINECS编号]

212-349-8

[分子式]

C21H28O2

[分子量]

312.45

[熔点]

206℃

[沸点]

459.1°C at 760 mmHg

[密度]

2.32E-10mmHg at 25°C

[闪点]

195.4°C

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左炔诺孕酮是应用较广的一种口服避孕药。它可以抑制排卵并阻止孕卵着床,同时使宫颈黏液浓度增大,阻止精子前进。服用左炔诺孕酮可能会造成轻微的呕吐、恶心,以及女性下次月经周期不规则。
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该品与炔雌醇组成复合片或双相片、三相片,用作短效口服避孕药,通过改变剂型可用作多种长效避孕药。口服吸收迅速,经O.5~2小时血浓度达峰值,T1/2为10~24小时。蛋白结合率93~95%,生物利用度100%。较多分布在肝、肾、卵巢及子宫,代谢物主要以葡萄糖醛酸盐和硫酸盐形式从尿和粪便中排泄。与炔雌醇组成复合片或双相片、三相片可作为短效口服避孕药。复合片降低高密度脂蛋白较明显,双相片、三相片则影响较小;由于三相片每周期减少该品用量约40%,不良反应少。该品是目前国际上应用最广泛的一种口服避孕药,用于妇女避孕。其埋植剂自1983年在芬兰上市后,现已被多个国家批准使用。5.5万名埋植者的经验表明妊娠率非常低,5年累积约3.9%。
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 For more about us , please visit our site: https://afinechem.en.alibaba.com or https://afinepharm.en.alibaba.com/   supply high quality Levonorgestrel ,CAS 797-63-7 , active pharmaceutical ingredient        Levonorgestrel is a manufactured hormone used in a number of birth control methods. In pill form, sold under the brand name Plan B among others, it is useful within 120 hours as emergency birth control. It becomes less effective the longer after sex and only works before pregnancy has occurred. It is also combined with an estrogen to make combined oral birth control pill. Within an IUD, sold as Mirena among others, it is effective for long term prevention of pregnancy. An implantable form of levonorgestrel is also available in some countries. Common side effects include nausea, breast tenderness, headaches, and increased, decreased, or irregular menstrual bleeding. If used as a form of emergency contraception during pregnancy there is no evidence it affects the baby. It is safe to use during breastfeeding. Birth control that contains levonorgestrel will not change the risk of sexually transmitted infections. It works mostly by decreasing ovulation and closing off the cervix to prevent the passage of sperm.      
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