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1264-72-8
1264-72-8结构式1264-72-8结构式
目录
基本信息
[英文名称]

colistin sulfate

[英文别名]

Colistin Sulphate; n-[3-amino-1-[[1-[[3-amino-1-[[6,9,18-tris(2-aminoethyl)-3-(1-hydroxyethyl)-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]carbamoyl]propyl]carbamoyl]-2-hydroxy-propyl]carbamoyl]propyl]-5-methyl-heptanamide sulfate; N-[(2S)-4-amino-1-{[(2S,3R)-1-{[(2S)-4-amino-1-oxo-1-{[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-3-[(1R)-1-hydroxyethyl]-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl]amino}butan-2-yl]amino}-3-hydroxy-1-oxobutan-2-yl]amino}-1-oxobutan-2-yl]-6-methyloctanamide sulfate (1:1); N-[(1S)-3-amino-1-{[(1S,2R)-1-{[(1S)-3-amino-1-{[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-3-[(1R)-1-hydroxyethyl]-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl]carbamoyl}propyl]carbamoyl}-2-hydroxypropyl]carbamoyl}propyl]-5-methylheptanamide

[CAS]

1264-72-8

[EINECS编号]

215-034-3

[分子式]

C52H98N16O13

[分子量]

1155.4339

[熔点]

200-220℃

[沸点]

1537.3°C at 760 mmHg

[密度]

0mmHg at 25°C

[闪点]

883.5°C

CAS号码1264-72-8 推荐供应商
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白色粉末,含量796% 杭州鼎燕化工有限公司位于中国东南沿海、浙江省会城市杭州的下沙经济开发区,是一家专业从事医药原料、医药中间体、精细化工及生化试剂等高新技术产品开发、销售和自营进出口融于一体的现代化民营企业。公司自创建以来坚持走“科技创新”的发展道路,高度重视科技创新研究开发工作,公司高品质产品畅销北美、西欧、东南亚以及中南美洲等六十多个国家和地区。目前与欧洲、美国、希腊、德国、伊朗、俄罗斯、韩国、印度等多个国家的制药企业建立了长期稳定的合作关系,以我们严谨的态度和诚挚的服务赢得了客户的信任和美誉。
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肠道疾病抗生素
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用途 :主要用于防治敏感菌的感染和促进畜禽生长。
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Colistin Sulfate 10% Colistin Sulfate is an antibiotic medicine. Mainly applied in pigs feed, chickens’ feed and cows’ feed. It can significantly stimulate growth of young animals and therefore enhance feed conversion and increase culture benefits.Prevention of infectious gastroenteritis of livestock, prevent and cure intestinal diseases caused by E.coli, Pseudomonas aeruginosa, Salmonella and other G- bacteria   Name of Active Substance: Colistin Sulfate Chemical Structure:                   CAS NO.: 1264-72-8 Formual: 2(C52H98N16O13).5(H2SO4)   Molecular Weight: 2801.27   Physical Properties Appearance: light yellow granule Cotent: 10% Loss on drying: ≤10.0% Particle size: 100% through 20 mesh sieves;   Storage and Stability The product should be contained in unopened original package, protected from light in a dry place at low temperature ( ≤15℃ ). Once it is opened, please use it up in a short time. The shelf life is 24 months for the unopened product stored in recommended condition.    Packaging Inside: vacauumed aseptic PE bags, 25kg per bag. Outside: kraft paper bag Packages size can also be offered according to customer requirement  
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可电话联系,了解更多详细
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Colistin is a peptide antibiotic widely used as a food additive in animal farming, specially swine and poultry, and also has been applied in human medicine to treat infections caused by multiresistant gram-negative bacteria strains. 粘菌素是广泛用作动物养殖,特别是猪和禽类的食品添加剂的肽抗生素,也被应用于人类药物,治疗由多重革兰氏阴性菌株引起的感染。
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硫酸粘杆菌素 EP 20千克/桶 GMP/DMF认证 主要用于敏感菌感染,如败血症、急性肠炎、尿路感染等
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硫酸粘杆菌素由多粘杆菌产生,对革兰氏阴性菌有较强的抗菌作用,用于治疗革兰氏阴性菌引起的肠道疾病,用作饲料添加剂,且有明显促生长作用。和磺胺嘧啶效果合用较好。
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粘菌素是一种多肽类抗生素,通过破坏细菌的细胞膜,导致细胞通透性的改变和细胞内物质的泄漏,对易感菌株产生杀菌作用。主要针对革兰氏阴性细菌有效,如肠杆菌科,特别是大肠杆菌。
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硫酸粘菌素(Colistin Sulphate,又称硫酸粘杆菌素、硫酸抗敌素、克利斯汀(Colistin)、多粘菌素E(Polymyxin E)、抗敌素等)分子式为C52H98N16O13・2H2SO4,分子量为1352。纯品为白色或类白色粉末,易溶于水。预混剂为浅褐色或褐色颗粒或粉末。易溶于水,耐热, 消化道不易吸收,
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含量:99%;
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400十亿/桶;20公斤/桶;
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White powder.
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 For more about us , please visit our site: https://afinechem.en.alibaba.com or https://afinepharm.en.alibaba.com/   COLISTIN SULPHATE  CAS  1264-72-8        Appearance: Powder Molecular Weight: 2801.27 Density: g/cm3 Boiling Point: 1536.8°Cat760mmHg Melting Point: 200-220℃ Flash Point: 883.3°C Storage Temperature: 2-8°C Refractive index: 1.575 Usage: Cyclic polypeptide antibiotic produced by Bacillus polymyxa. Complex mixture of at least 30 components, primarily colistins A and B. [a]D= -65?(c= 1, **) LOD: 3%        
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白色或近白色粉末,无臭、味苦有引湿性,易溶于水,微溶于甲醇、乙醇,溶于丙酮、乙醚等,游离碱微溶于水。在PH3-7.5范围内稳定。
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粉末
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产品介绍:
  Hot sell Colistin Sulphate/1264-72-8   1.CAS NO:1264-72-8   2.Color:white   3.Standard:EP   4.Packing:20kg/drum     Products:Colistin sulphate is an antibiotic class medicine. Used to treat gastro-intestinal diseases caused by gram-negative bacilli, and certain growth-promoting effect.   Executive Standard: European Pharmacopoeia Standard (EP4).   welcome to contact with us to develop mutual benefical business relationship   Test Specification Characteristics White or almost white powder Identification Meets EP specification PH 4.0 ~ 6.0 Loss on drying ≤3.5% Optical rotation -63° ~ -73° Sulphated ash ≤1.0% Sulphate (dried basis) 16.0% ~ 18.0% Content (Dry basis HPLC) Colistin E1-I≤10%   Colistin E1-7MOA≤10%   Colistin E3≤10%   E1+ E2+E3+E1-I+E1-7MOA≥77.0% Related substances Any impurity≤4.0%   Total impurity≤23.0% Potency(Moisture basis) ------- Potency (Dried basis) ≥19000IU/mg   Melting point: 200-220 DHS C   Descriptors: sticky coli sulfuric acid meat (1264-72-8)   Traits:   1. Outside its shape as a white powder, has hygroscopic, soluble in water.   2. White mouse or rat LD50 > 12 g through the mouth/kg. 2. Premix in room temperature preservation 2 years, titer is kept in the above 94.5%; Mixing feed, room temperature preservation 8 weeks; Titer drop about 20% ~ 30%.                    
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硫酸粘杆菌素属窄谱抗生素。主要对革兰氏阴性菌有强大抗菌作用,敏感菌有绿脓杆菌、大肠杆菌、肠杆菌属、克雷伯氏菌属、沙门氏菌属、志贺氏菌属、巴斯德氏菌和弧菌等。
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