基本信息 中文名称：格列本脲 中文别名：优降糖；达安疗；达安宁；乙磺己脲；优格鲁康；氯磺环己脲；N-(2-(4-((((环己氨基)羰基)氨基)磺酰基)苯基)乙基)-2-甲氧基-5-氯苯甲酰胺 英文名称：Glibenclamide 英文别名：glybenclamide；glyburide usp；Glibenclamide；Glyburide；5-chloro-n-(2-(4-((((cyclohexylamino)carbonyl)-amino)sulfonyl)phenyl)-ethyl)-2-methoxybenzamide；5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide；5-chloro-2-methoxy-N-[2-[4-(phenylcarbamoylsulfamoyl)phenyl]ethyl]benzamide；HB-419；maninil；adiab CAS号：10238-21-8 EINECS号：233-570-6 分子式：C23H28ClN3O5S 分子量：494.01 精确质量：493.14400 PSA：121.98000 LogP：5.89520 物化性质 密度：1.376g/cm3 剂型：原料药 外观：白色晶体粉末。 熔点：173-175°C 折射率：1.628 稳定性：常温常压下稳定 储存条件：库房低温通风干燥 含量：99% 可溶性：不溶于水，微溶于乙醇、丙酮、氯仿。

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   For more about us , please visit our site:https://afinechem.en.alibaba.com  https://afinechem.en.alibaba.com    https://afinechem.en.alibaba.com  High Quality Glibenclamide CAS NO.:10238-21-8active pharmaceutical ingredient   Appearance: white or almost white crystalline podwer Molecular Weight: 494 Density: 1.36 g/cm3/sup> Boiling Point: °Cat760mmHg Melting Point: 173-175°C Flash Point: °C Storage Temperature: 2-8°C Refractive index: 1.628 Solubility: Practically insoluble in **, sparingly soluble in methylene chloride, slightly soluble in ethanol (96%) and in methanol. Practically insoluble in ether. It dissolves in dilute solutions of alkali hydroxides. Biological Activity: ATP-dependent K + channel (K ATP ) and CFTR Cl - channel blocker. Inhibits K ATP currents in the pancreas, causing an increase in intracellular Ca 2+ and insulin secretion. Inhibits recombinant CFTR Cl- channels with an IC 50 of 20 μ M. Stability: Stable at normal temperatures and pressures. Usage: A second generation sulfonylurea with hypoglycemic activity Safety Data of 10238-21-8    

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