序列:ARTKQTARKS TGGKAPRKQL ATKAARKSAP ATGGVK(me2)KPHR YRPGTVALRE IRRYQKSTEL LIRKLPFQRL
VREIAQDFKT DLRFQSSAVM ALQEACEAYL VGLFEDTNLC AIHAKRVTIM PKDIQLARRI RGERA
Histone modifications are associated with distinct transcription states and serve as heritable epigenetic markers for chromatin structure and function.In humans, H3K36 methylation is catalysed through the activities of eight distinct enzymes, while SETD2/HYPB uniquely catalyses the methylation of H3K36.