eplerenone依普利酮

更新时间：2018-03-23

CAS号：107724-20-9

药典：中国药典,美国药典,英国药典,欧洲药典,日本药典,企业标准

级别：药用级

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详细描述

主要销售市场：北美洲,中/南美洲,西欧,东欧,大洋洲,亚洲,中东,非洲
提供样品：否

产品描述：

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high quality Eplerenone Powder CAS 107724-20-9, pharmaceutical ingredient

Chemical Properties

Appearance:

White Solid

Molecular Weight:

414.49

Density:

1.31g/cm³

Boiling Point:

597.9°Cat760mmHg

Melting Point:

241-243oC

Flash Point:

259.5°C

Refractive index:

1.587

Solubility:

Very slightly soluble in **, with its solubility essentially pH dependent
In **, 2.1X10-3 mg/L at 25 deg C (est)

Biological Activity:

Selective mineralocorticoid (aldosterone) receptor antagonist (IC 50 = 360 nM). Displays > 27-fold selectivity over androgen, progesterone and estrogen receptors (IC 50 > 10 μ M). Orally active antihypertensive in vivo .

Usage:

Selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoi

Safety Data of 107724-20-9

HOT PRODUCT

以下信息来自CAS号查询大全，前往了解更多：107724-20-9

eplerenone依普利酮CAS号：107724-20-9

eplerenone依普利酮分子式： C24H30O6

107724-20-9

eplerenone依普利酮英文名称： eplerenone

eplerenone依普利酮英文同义词： pregn-4-ene-7,21-dicarboxylic acid 9,11-epoxy-17-hydroxy-3-oxo gamma-lactone methyl ester; the intermediates; methyl (4aS,4bR,6aS,7R,9aS,10R)-4a,6a-dimethyl-2,5'-dioxo-2,4,4',4a,5',5a,6,6a,8,9,9a,9b,10,11-tetradecahydro-3H,3'H-spiro[cyclopenta[7,8]phenanthro[4b,5-b]oxirene-7,2'-furan]-10-carboxylate; methyl (4aS,4bR,5aS,6aS,7R,9aS,9bR,10R)-4a,6a-dimethyl-2,5'-dioxo-2,4,4',4a,5',5a,6,6a,8,9,9a,9b,10,11-tetradecahydro-3H,3'H-spiro[cyclopenta[7,8]phenanthro[4b,5-b]oxirene-7,2'-furan]-10-carboxylate; methyl (4aS,4bR,5aR,6aS,7S,9aS,9bR,10R)-4a,6a-dimethyl-2,5'-dioxo-2,4,4',4a,5',5a,6,6a,8,9,9a,9b,10,11-tetradecahydro-3H,3'H-spiro[cyclopenta[7,8]phenanthro[4b,5-b]oxirene-7,2'-furan]-10-carboxylate; methyl (4aS,4bR,5aR,6aS,7R,9aS,9bR,10R)-4a,6a-dimethyl-2,5'-dioxo-2,4,4',4a,5',5a,6,6a,8,9,9a,9b,10,11-tetradecahydro-3H,3'H-spiro[cyclopenta[7,8]phenanthro[4b,5-b]oxirene-7,2'-furan]-10-carboxylate

eplerenone依普利酮分子量： 414.4914

eplerenone依普利酮沸点： 597.933°C at 760 mmHg

eplerenone依普利酮密度： 0mmHg at 25°C

eplerenone依普利酮闪点： 259.474°C

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