三乙基硼氢化锂THF

性质 Properties

本品的化学活性很高。闪点是-17℃。在常温下，它能迅速和水、盐酸、甲磺酸以及甲醇等反应，放出氢气。它可溶于四氢呋喃等醚类溶剂。它的四氢呋喃溶液在氮气中非常稳定，但若放置于空气或湿气中，并迅速分解。本品是一种极强的亲核还原剂，其还原能力比其母体硼氢化锂强得多，在许多反应中也优于氢化铝锂。

This product has very high chemical activity. Flash point:-17℃. At room temperature, it can rapidly react with **, hydrochloric acid, methanesulfonic acid and methanol to release hydrogen. It can be dissolved in THF and other ether solvents. Its THF solution is very stable under nitrogen, but will be decomposed very quickly in air or moisture. This product is an extremely strong nucleophilic reducer, and its reducing power is much stronger than its parent company, LiBH4. In many reactions, it is also better than LiAlH4.

用途 Usage

在有机合成中用作还原剂，它能还原醛酮、羟酸、羟酸衍生物、伯酰胺、叔酰胺、脂肪族硝基化合物、酯、内酯、含硫化合物、磺酸、卤代芳烃、环氧化物等，也可以在区域或是立体选择还原剂中也显示出优良的特性，被誉为“超氢化物”。

Used as reducing agent in organic synthesis, it can reduce aldehyde ketone, carboxylic acids, carboxylic acid derivatives, primary amides, tertiary amides, aliphatic nitro compounds, esters, lactones, sulphur compounds, sulfonic acid, halogenated aromatics and epoxide, etc., It shows good regional selectivity or stereoselectivity as a reductant, which is called ”super hydride”.