Gefitinib吉非替尼

更新时间：2018-03-14

CAS号：184475-35-2

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Gefitinib CAS 184475-35-2

Chemical Properties Appearance: Light-Yellow Crystalline Powder Molecular Weight: 446.9 Density: 1.322g/cm³ Boiling Point: 586.8 °C at 760 mmHg Melting Point: 119-120 Flash Point: 308.7 °C Refractive index: 1.621 Biological Activity: Orally active, selective inhibitor of EGFR tyrosine kinase (IC 50 = 23-79 nM). Shows minimal activity against ErbB2, KDR, c-flt, PKC, MEK and ERK-2. Blocks EGFR autophosphorylation and inhibits tumor growth in mice bearing a range of human xenografts. Usage: An antineoplastic Safety Data of 184475-35-2

Chemical Properties

Appearance:

Light-Yellow Crystalline Powder

Molecular Weight:

446.9

Density:

1.322g/cm³

Boiling Point:

586.8 °C at 760 mmHg

Melting Point:

119-120

Flash Point:

308.7 °C

Refractive index:

1.621

Biological Activity:

Orally active, selective inhibitor of EGFR tyrosine kinase (IC 50 = 23-79 nM). Shows minimal activity against ErbB2, KDR, c-flt, PKC, MEK and ERK-2. Blocks EGFR autophosphorylation and inhibits tumor growth in mice bearing a range of human xenografts.

Usage:

An antineoplastic

Safety Data of 184475-35-2

HOT PRODUCT

以下信息来自CAS号查询大全，前往了解更多：184475-35-2

Gefitinib吉非替尼CAS号：184475-35-2

Gefitinib吉非替尼分子式： C22H24ClFN4O3

184475-35-2

Gefitinib吉非替尼英文名称： Iressa

Gefitinib吉非替尼英文同义词： GEFITINIB; AKOS 91371; n-(3-chloro-4-fluoro-phenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine; N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine; ZD 1839; 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-; Gefitinib(TINIBS); Gefitinib, Iressa, ZD1839; Gefitinib Base

Gefitinib吉非替尼分子量： 446.9024

Gefitinib吉非替尼熔点： 119-120

Gefitinib吉非替尼沸点： 586.755°C at 760 mmHg

Gefitinib吉非替尼密度： 0mmHg at 25°C

Gefitinib吉非替尼闪点： 308.659°C

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