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Product Details
Doxycycline Hcl is antibacterial spectrum is very close to Tetracycline and Terramycin, but it has better effect, be sensitive to the Staphylococcus Aureus of tetracycline-resistant, oxytetracycline, long lasting time.It is often used in Senile Chronic Bronchitis, respiratory tract infection, lung infection, acute tonsillitis, mycoplasma pneumonia, urinary tract infection, blood poisoning, bacillary dysentery, acute lymphadenitis, etc. It is very popular to Nephropathy patient because of its unobvious poisoning for kidney.
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Items |
Specifications |
Results |
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Appearance |
Yellow crystalline powder |
Conforms |
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Identification |
TLC |
Conforms |
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sulphuric acid reaction a yellow colour develops |
Conforms |
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it gives reaction of chlorides |
Conforms |
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PH |
2.0~3.0 |
2.3 |
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Specific absorbance |
at 349nm e(1%) 300~355 |
320 |
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Specific optical rotation |
-105 ~ -120° |
-110° |
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Heavy metals: |
≤50ppm |
< 20ppm |
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Light-absorbing impurities |
at 490nm ≤0.07 |
0.03 |
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Related substances |
6-epidoxycycline ≤2.0% metacycline ≤2.0% 4-epidoxycycline ≤0.5% (ep5) 4-epi-6-epidoxycycline ≤0.5% (ep5) oxytetracycline ≤0.5% (ep5) any other impurity ≤0.5% not identified impurities ≤0.1% (ep5) |
1.6% 0.1% Not found Not found Not found Not found Not found |
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Ethanol |
4.3~6.0% (m/m) |
4.5% |
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Sulphated ash |
≤0.4% |
0.05% |
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Water |
1.4~2.8% |
1.8% |
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Assay |
95.0~102.0% ( c22h25cln2o8) based on anhydrous, ethanol-free substance |
98.6% |
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Conclusion |
Conform with USP32 |
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Doxycycline HyclateCAS号：24390-14-5
Doxycycline Hyclate分子式： C22H26N2O9
Doxycycline Hyclate中文名称：盐酸强力霉素
Doxycycline Hyclate中文同义词：多西环素(强力霉素);盐酸多西环素USP级;6-甲基-4-(二甲氨基)-3,5,10,12,12a-五羟基-1,11-二氧代-1,4,4a,5,5a,6,11,12a-八氢-2-并四苯甲酰胺盐酸盐;脱
Doxycycline Hyclate英文名称： Doxycycline hyclate
Doxycycline Hyclate英文同义词： DOXYCYCLINE HYDRATE;4-(DIMETHYLAMINO)-1,4,4 ALPHA,5,5 ALPHA,6,11,12 ALPHA-OCTAHYDRO-3,5,10,12,12 ALPHA-PENTAHYDROXY-6-METHYL-1,11-DIOXO-2-NAPHTHACENECARBOXAMIDE, MONOHYDRATE;4-(DIMETHYLAMINO)-1,4,4A,5,5A,6,11,12A-OCTAHYDRO-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-2-NA;Doxycycline monohydrate BP2000/Ph Eur 4/USP25;DOXYCYCLINE HYDROCHLORIDE, VETRANAL;Doxycycline Hyclate USP;DOXYCYCLINE HYCLATE USP GRADE;2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, (4S,4aR,5S,5aR,6R,12aS)-, compd. with ethanol (2:1), monohydrate
Doxycycline Hyclate分子量： 462.45
Doxycycline Hyclate熔点： 206-209?C (dec.)
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