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Domperidone CAS 57808-66-9
Appearance:
white powder
Molecular Weight:
425.91126
Density:
1.341 g/cm3
Melting Point:
242.5 oC
Storage Temperature:
Keep tightly closed.
Solubility:
DMSO: >10 mg/mL
Biological Activity:
Peripheral dopamine D 2 -like receptor antagonist that does not readily cross the blood brain barrier. Displays gastroprokinetic and antiemetic properties; increases the frequency and duration of antral and duodenal contractions and protects from apo**-induced emesis (ED 50 values are 0.003 and 0.03 mg/kg for i.v. and oral administration respectively).
Stability:
Stable. Incompatible with strong oxidizing agents.
Usage:
Peripheral dopamine receptor antagonist that does not cross the blood-brain barrier; anti-emetic.
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