小型化全自动制备一体机Miniaturized automatic preparation machine

一、产品简介

该产品为常州东曦自动化科技有限公司为适应市场需求而研发生产的定制产品。主要目的是为了解决当前中小型制备自动化程度不高的问题，实现完全自动化操作，从而节省人力物力，向工业4.0迈进。主要适用于DAC200及以下色谱柱。

前期本公司已经对多家客户的相关产品进行了升级改造，并保持了良好的沟通，积累了一定的实际生产经验，为本产品的设计制造奠定了基础。在设备运行过程中，客户在肯定设备功能的基础上，提出了诸多改进意见，本公司根据客户建议对设备进行优化设计，以满足客户工厂批量生产的要求。

二、系统组成

1、PLC控制系统及软件

      （1）能控制多台泵进行梯度洗脱（即泵能以任意流速任意比例运行，例如A泵从0%至100%同时B泵从100%至0%，但是总值为100%；或者A泵从17%至88%同时B泵从83%至12%，流速总和为设定流速之内任意数值），也可单独控制每台泵。

（2）根据预先设计好的工作模式进行自动进样、洗脱、收集工作，并可无限循环运行。

（3）控制进样泵精准进样。

（4）控制阀门进行工作模式切换及收集。

（5）控制检测器进行信号收集及反馈，实现可根据时间及峰高进行自动切换收集。                         

2 溶剂泵。根据客户实际需求选择1台或者多台泵。

3 进样泵。根据客户实际需求选择，数量1台，用于进样。

4 检测器。根据客户实际需求选择。

5 收集系统。根据客户实际需求选择。与液体接触部分材质为316L、PTFE、POM或者PEEK。

6 工作模式切换阀。根据客户实际需求选择。与液体接触部分材质为316L，PTFE、POM或者PEEK。

7 装柱专用手动阀。两位三通球阀3个，通径4mm，耐压10Mpa。与液体接触部分材质为316L，PTFE、POM或者PEEK。

8 在线过滤器。安装在进色谱柱之前。可以选装1个或者多个。

9 框架及管路。框架为铝型材拼接或者304焊接组装框架。管路为无缝钢管，材质均为316L。

1. Product introduction

This product is a customized product developed and produced by Changzhou Dongxi Automation Technology Co., Ltd. to meet market demand. The main purpose is to solve the current problem of low degree of automation in small and medium-sized preparations, and to achieve fully automated operation, so as to save manpower and material resources and move towards Industry 4.0. It is mainly suitable for DAC200 and below columns.

In the early stage, the company has upgraded the related products of many customers, maintained good communication, accumulated certain practical production experience, and laid the foundation for the design and manufacture of this product. In the process of equipment operation, the customer on the basis of affirming the function of the equipment, put forward a lot of improvement suggestions, the company according to the customer's suggestions to optimize the design of the equipment to meet the requirements of the customer's factory mass production.

Second, the system composition

1. PLC control system and software

(1) It can control multiple pumps for gradient elution (that is, the pump can operate at any flow rate in any proportion, for example, pump A from 0% to 100% and pump B from 100% to 0%, but the total value is 100%; or pump A from 17% to 88% and pump B from 83% to 12%, the sum of the flow rates is any value within the set flow rate), and each pump can also be controlled separately.

(2) Automatic sampling, elution and collection are carried out according to the pre-designed working mode, and can be operated in infinite cycles.

(3) Control the injection pump to inject accurately.

(4) Control the valve to switch and collect the working mode.

(5) Control the detector for signal collection and feedback, and realize automatic switching and collection according to time and peak height.                         

2 Solvent pumps. Choose one or more pumps according to the actual needs of customers.

3 Injection pumps. According to the actual needs of customers, the quantity is 1 set, which is used for injection.

4 Detectors. Choose according to the actual needs of customers.

5 Collection system. Choose according to the actual needs of customers. The parts that come into contact with the liquid are made of 316L, PTFE, POM or PEEK.

6. Working mode switching valve. Choose according to the actual needs of customers. The material for contact with liquids is 316L, PTFE, POM or PEEK.

7. Special manual valve for column installation. There are 3 two-position three-way ball valves, with a diameter of 4mm and a pressure resistance of 10Mpa. The material for contact with liquids is 316L, PTFE, POM or PEEK.

8 Online filters. Installed before the incoming column. One or more can be optionally installed.

9 Frame and tubing. The frame is aluminum profile splicing or 304 welded assembly frame. The pipes are seamless steel pipes, and the materials are all 316L.