FINGOLIMOD盐酸芬戈莫德

更新时间：2018-03-27

CAS号：162359-56-0

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Fingolimod hydrochloride(4-fingolimod intermediate),CAS:162359-56-0 ,active pharmaceutical ingredient

FTY720 is a derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analogue of Sphingosine. FTY720 is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs. FTY720 us reported to be phosphorylated by sphingosine kinase to FTY720-P, which has been shown to potently stimulate GTPgS binding activity in S1P-transfected CHO cells (EC50 = 210 pM, 4.9 nM, 4.3 nM, and 1 nM for S1P1, S1P3, S1P4 and S1P5, respectively).

FTY720 is a derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analogue of Sphingosine. FTY720 is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs. FTY720 us reported to be phosphorylated by sphingosine kinase to FTY720-P, which has been shown to potently stimulate GTPgS binding activity in S1P-transfected CHO cells (EC50 = 210 pM, 4.9 nM, 4.3 nM, and 1 nM for S1P1, S1P3, S1P4 and S1P5, respectively).

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FINGOLIMOD盐酸芬戈莫德CAS号：162359-56-0

FINGOLIMOD盐酸芬戈莫德分子式： C19H33NO2

162359-56-0

FINGOLIMOD盐酸芬戈莫德英文名称： Fingolimod hydrochloride

FINGOLIMOD盐酸芬戈莫德英文同义词： 2-Amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol hydrochloride; Fingolimod HCl; 2-(4-octylphenylethyl)-2-aminopropane-1,3-diol HCL; 2-amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol hydrochloride (1:1); 2-amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol; 2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol

FINGOLIMOD盐酸芬戈莫德分子量： 307.4708

FINGOLIMOD盐酸芬戈莫德沸点： 479.5°C at 760 mmHg

FINGOLIMOD盐酸芬戈莫德密度： 5.28E-10mmHg at 25°C

FINGOLIMOD盐酸芬戈莫德闪点： 243.8°C

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