Lovastatin

更新时间：2018-03-28

CAS号：75330-75-5

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Lovastatin 99%CAS NO.:75330-75-5 ,active pharmaceutical ingredient

Chemical Properties Appearance: White solid Molecular Weight: 404.54 Density: 1.12 g/cm³ Boiling Point: 559.2 oC at 760 mmHg Melting Point: 175℃ Flash Point: 185.3 oC Storage Temperature: 2-8°C Refractive index: 320 ° (C=0.5, CH3CN) Solubility: 0.0004 mg/mL at 25 oC Biological Activity: Potent, competitive inhibitor of HMG-CoA reductase (K i = 0.6 nM) therefore decreases cholesterol biosynthesis, in vitro and in vivo . Decreases CDK2, 4, 6 and cyclin E levels and induces G1 arrest and apoptosis in tumor cell lines in vitro . Usage: An antihypercholesterolemic agent. A fungal metabolite, which is a potent inhibitor of HMG-CoA reductase Safety Data of 75330-75-5

Chemical Properties

Appearance:

White solid

Molecular Weight:

404.54

Density:

1.12 g/cm³

Boiling Point:

559.2 oC at 760 mmHg

Melting Point:

175℃

Flash Point:

185.3 oC

Storage Temperature:

2-8°C

Refractive index:

320 ° (C=0.5, CH3CN)

Solubility:

0.0004 mg/mL at 25 oC

Biological Activity:

Potent, competitive inhibitor of HMG-CoA reductase (K i = 0.6 nM) therefore decreases cholesterol biosynthesis, in vitro and in vivo . Decreases CDK2, 4, 6 and cyclin E levels and induces G1 arrest and apoptosis in tumor cell lines in vitro .

Usage:

An antihypercholesterolemic agent. A fungal metabolite, which is a potent inhibitor of HMG-CoA reductase

Safety Data of 75330-75-5

HOT PRODUCT

以下信息来自CAS号查询大全，前往了解更多：75330-75-5

LovastatinCAS号：75330-75-5

Lovastatin分子式： C24H36O5

75330-75-5

Lovastatin英文名称： Lovastatin

Lovastatin英文同义词： mevlor ; msd803 ; oxy)-1-naphthaleneheptanoicaciddelta-lactone ; LOVASTATION ; LOVASTIN ; LOVALIP ; MEVINOLIN; 8-[2-(4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2-methylbutanoate; (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate; (1S,3R,7S,8S)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate

Lovastatin分子量： 404.5396

Lovastatin熔点： 175℃

Lovastatin沸点： 559.198°C at 760 mmHg

Lovastatin密度： 0mmHg at 25°C

Lovastatin闪点： 185.304°C

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