Chemical Properties
Appearance:
white to off-white crystalline powder
Molecular Weight:
461.01
Boiling Point:
682 °C at 760mmHg
Melting Point:
183.5-184.5 deg C /Losartan/
Flash Point:
366.3 °C
Solubility:
Freely soluble in **, soluble in alcohols, and slightly soluble in common organic solvents, such as acetonitrile and methyl ethyl ketone.
Biological Activity:
Selective non-peptide angiotensin AT 1 receptor antagonist. Inhibits the contractile effects of angiotensin II on rabbit aorta and jugular vein (pA 2 = 8.27). Orally active antihypertensive agent.
Usage:
Losartan potassium (CAS NO.124750-99-8) can be used as a nonpeptide angiotensin II AT1-receptor antagonist.
Safety Data of 124750-99-8
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