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Carboplatin CAS 41575-94-4
Chemical Properties
Appearance:
white crystalline powder
Molecular Weight:
373.26436
Density:
g/cm3
Boiling Point:
366.4oCat 760 mmHg
Melting Point:
228-230oC
Flash Point:
189.6oC
Storage Temperature:
Store at RT
Solubility:
Soluble
Biological Activity:
Antitumor agent that forms platinum-DNA adducts. Causes intra- and interstrand DNA crosslinks blocking DNA replication and transcription. Enhances radiation-induced single-strand DNA breakage and displays lower nephrotoxicity than analog cisplatin (cis-Diaminodichloroplatinum ).
Stability:
Stable. Incompatible with strong oxidizing agents.
Usage:
Analog of Cisplatin with reduced nephrotoxicity. Antineoplastic
