卡博替尼

中文名称卡博替尼中文同义词XL184(博卡替尼);XL-184(卡博替尼);卡博替尼碱;卡博替尼100MG;N-[4-[(6,7-二甲氧基-4-喹啉基)氧基]苯基]-N'-(4-氟苯基)-1,1-环丙烷二甲酰胺;卡赞替尼;卡博替尼;苹果酸盐CABXL-184英文名称Cabozantinib英文同义词Carbozantinib;Cabozantinib(XL184Malate);Cabozantinib(XL184,BMS-907351);N-(4-(6,7-diMethoxyquinolin-4-yloxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxaMide(CAChemicalbookS：849217-68-1);XL-186;1,1-cyclopropanedicarboxamide,n'-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-n-(4-fluorophenyl)-;N-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamideCabozantinib(XL184,BMS-907351);Cabozantinib,>=98%CAS号849217-68-1分子式C28H24FN3O5分子量501.51EINECS号692-846-8

熔点212-215°C沸点758.1±60.0°C(Predicted)密度1.396储存条件-20°C溶解度SolubleinDMSO形态Whitepowder.酸度系数(pKa)13.86±0.70(PredChemicalbookicted)颜色White稳定性Stablefor1yearfromdateofpurchaseassupplied.SolutionsinDMSOmaybestoredat-20°Cforupto1month.