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Cephradine
1.CAS NO.38821-53-3
2.M.F:C16H21N3O5S
3.M.W:367.42
4.Appearance:white powder crystal powder. Soluble in water.
Specifications
|
ITEMS |
STANDARD |
RESULTS |
|
Appearance |
White to off-white, crystalline powder. Sparingly soluble in water, very slightly soluble in alcohol and in chloroform, practically insoluble in ether. |
Off-white powder |
|
Solubility |
|
Complies |
|
Identification |
The IR spectrum confirm to that of reference standard |
Complies |
|
Crystallinity |
Meet the requirements |
Complies |
|
PH |
3.5 to 6.0 |
4.8 |
|
Specific optical rotation |
+80.0° to +90.0° |
+86° |
|
Water |
Not more than 4.3% |
0.043 |
|
Limit of Cephalexin |
Not more than 5.0% |
0.013 |
|
Related substance |
|
|
|
7-ADCA |
NMT 1.0% |
0.00002 |
|
Any other impurity |
NMT 2.0% |
0.014 |
|
Total |
NMT 2.5% |
0.015 |
|
N,N-Dimethylaniline |
Not more than 20 ppm |
Not found |
|
Acetone |
NMT 0.3% |
0.000002 |
|
Dichloromethane |
NMT 0.06% |
Not found |
|
Sulphated ash |
NMT 0.2% |
0.0008 |
|
Assay |
99.0% to 105.0% |
|
CephradineCAS号：38821-53-3
Cephradine分子式： C16H19N3O4S
Cephradine英文名称： Cefradine
Cephradine英文同义词： CEPHRADINE COMPACTED; CEPHRADINE MICRONISED POWDER; Cephradine; Anspor; Velosef; (6r-(6alpha,7))-((amino-1,4-cyclohexadien-1-ylacetyl)amino)-3-methyl-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid; (6R,7R)-7-{[(2R)-2-amino-2-(cyclohexa-1,4-dien-1-yl)acetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; (7R)-7-{[(2R)-2-amino-2-cyclohexa-1,4-dien-1-ylacetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CephradineEINECS号： 254-137-8
Cephradine分子量： 349.4048
头孢菌素类
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