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Hot sell Colistin Sulphate/1264-72-8
1.CAS NO:1264-72-8
2.Color:white
3.Standard:EP
4.Packing:20kg/drum
Products:Colistin sulphate is an antibiotic class medicine. Used to treat gastro-intestinal diseases caused by gram-negative bacilli, and certain growth-promoting effect.
Executive Standard: European Pharmacopoeia Standard (EP4).
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Test |
Specification |
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Characteristics |
White or almost white powder |
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Identification |
Meets EP specification |
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PH |
4.0 ~ 6.0 |
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Loss on drying |
≤3.5% |
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Optical rotation |
-63° ~ -73° |
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Sulphated ash |
≤1.0% |
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Sulphate (dried basis) |
16.0% ~ 18.0% |
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Content (Dry basis HPLC) |
Colistin E1-I≤10% |
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Colistin E1-7MOA≤10% |
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Colistin E3≤10% |
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E1+ E2+E3+E1-I+E1-7MOA≥77.0% |
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Related substances |
Any impurity≤4.0% |
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Total impurity≤23.0% |
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Potency(Moisture basis) |
------- |
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Potency (Dried basis) |
≥19000IU/mg |
Melting point: 200-220 DHS C
Descriptors: sticky coli sulfuric acid meat (1264-72-8)
Traits:
1. Outside its shape as a white powder, has hygroscopic, soluble in water.
2. White mouse or rat LD50 > 12 g through the mouth/kg. 2. Premix in room temperature preservation 2 years, titer is kept in the above 94.5%; Mixing feed, room temperature preservation 8 weeks; Titer drop about 20% ~ 30%.
Colistin SulphateCAS号：1264-72-8
Colistin Sulphate分子式： C52H98N16O13
Colistin Sulphate英文名称： colistin sulfate
Colistin Sulphate英文同义词： Colistin Sulphate; n-[3-amino-1-[[1-[[3-amino-1-[[6,9,18-tris(2-aminoethyl)-3-(1-hydroxyethyl)-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]carbamoyl]propyl]carbamoyl]-2-hydroxy-propyl]carbamoyl]propyl]-5-methyl-heptanamide sulfate; N-[(2S)-4-amino-1-{[(2S,3R)-1-{[(2S)-4-amino-1-oxo-1-{[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-3-[(1R)-1-hydroxyethyl]-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl]amino}butan-2-yl]amino}-3-hydroxy-1-oxobutan-2-yl]amino}-1-oxobutan-2-yl]-6-methyloctanamide sulfate (1:1); N-[(1S)-3-amino-1-{[(1S,2R)-1-{[(1S)-3-amino-1-{[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-3-[(1R)-1-hydroxyethyl]-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl]carbamoyl}propyl]carbamoyl}-2-hydroxypropyl]carbamoyl}propyl]-5-methylheptanamide
Colistin SulphateEINECS号： 215-034-3
Colistin Sulphate分子量： 1155.4339
Colistin Sulphate熔点： 200-220℃
Colistin Sulphate沸点： 1537.3°C at 760 mmHg
Colistin Sulphate密度： 0mmHg at 25°C
Colistin Sulphate闪点： 883.5°C
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