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绒促性素(HCG,Chorionic Gonadotrophin)

绒促性素(HCG,Chorionic Gonadotrophin)

更新时间:2023-03-23
CAS号:9002-61-3
药典:英国药典,欧洲药典
级别:药用级
详细描述
  • 主要销售市场:西欧,亚洲
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产品描述:

绒促性素(HCG)自将康孕妇尿中提取、精制而成的一种天然促性腺激素,具有类似黄体生成素的功能。对女性可促进卵泡的成熟及排卵,并维持黄体的功能。对男性,能剌激睾丸间质细胞的发育,增加雄激素分泌,促使睾丸下降和男性第二性征发育。与尿促性素合用,可模拟生理性的促黄体生成素高峰,而促发排卵。临床上绒促性素至今仍是**月经失调、无排卵性不孕症、先兆流产和习惯性活产、隐睾症、男性性功能低下等的**药物。此外,它还广泛应用于性保健,计划生育事业以及渔业和畜牧业的生产。

性状

白色或类白色粉末

鉴别

符合规定

活性

不少于5,000 IU/mg

水分

不多于5%

细菌内毒素

不多于0.01 EU/HCG IU

异常毒*性

符合规定 

残留溶剂

0.5%

人类免疫缺陷病毒I型和II型抗原

阴性

乙肝病毒表面抗原

阴性

丙肝病毒抗体

阴性

 HCG is a natural gonadotropin extracted and refined from the urine of healthy pregnant women, which has a function similar to luteinizing hormone. For women, the maturation and ovulation of follicles can be promoted, and the function of the yellow body is maintained. For men, it stimulates the development of interstitial cells in the testes, increases androgen secretion, and promotes testicular decline and the development of second sexual characteristics in men. In combination with menotrophin, it can simulate the peak of bio-rational provonomic serotoin and promote ovulation. Clinical chorionic gonadotrophin is still the preferred drug for the treatment of menstrual disorders, no ovulation infertility, pre-eclampsia and habitual live births, cryptotestism, and low male sexual function. In addition, it is widely used in sexual health care, family planning and fisheries and livestock production.

Appearance

White to yellowish-white powder

Identification

Conform with regulation

Activity

Not less than 5,000 IU/mg

Water

Not more than 5.0%

Bacterial endotoxins

Not more than 0.01 EU/HCG IU

Abnormal toxicity

Conform with regulation

Residual Solvent

0.5%

HIV I+II antigen

Negative

Hepatitis B surface antigen

Negative

HCV antibodies

Negative

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