吡柔比星

英文名称

Pirarubicin

英文别名

Pirarubicin [INN:JAN]; (2''R)-4'-O-Tetrahydropyranyladriamycin; (8S,10S)-10-((3-Amino-2,3,6-trideoxy-4-O-(2R-tetrahydro-2H-pyran-2-yl)-alpha-L-lyxo-hexopyranosyl)oxy)-8-glycoloyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione; 1609RB; 4'-O-Tetrahydropyranyladriamycin; 4'-O-Tetrahydropyranyldoxorubicin; Pirarubicina; Pirarubicina [Spanish]; Pirarubicine; Pirarubicine [French]; Pirarubicinum; Pirarubicinum [Latin]; THP-adriamycin; 5,12-Naphthacenedione, 10-((3-amino-2,3,6-trideoxy-4-O-(tetrahydro-2H-pyran-2-yl)-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S-cis)-; (1S,3S)-3,5,12-trihydroxy-3-(hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-4-O-[(2S)-tetrahydro-2H-pyran-2-yl]-alpha-L-lyxo-hexopyranoside; (3S)-3,5,12-trihydroxy-3-(hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-alpha-L-lyxo-hexopyranoside

CAS

72496-41-4

分子式

C32H37NO12

分子量

627.6357

说明书

【英文名称】 Pirarubicin

【其他名称】阿克拉霉素B，吡喃阿霉素，Aclacinomycin B，Therarubicin，THP

【性状】为白色至淡黄色冻干疏松块状物。

作用

主要用于恶性淋巴瘤、急性白血病、乳腺癌、泌尿道上皮癌(膀胱癌及输尿管癌)、卵巢癌，也可用于子宫颈癌、头颈部癌和胃癌。